First-half goals from Joe Cole and Nicolas Anelka kept Scolari's men at the top of the Barclays Premier League, and it could have been more but for the reflexes of Villa goalkeeper Brad Friedel.
• Scolari: My most satisfying win
The hosts, already without the services of Didier Drogba, Deco, Ricardo Carvalho and Michael Essien, were missing Alex from their starting line-up and then saw midfielder Cole limp off.
Anelka, struggling with muscle spasms before the match, was also taken off at the break meaning Franco di Santo was Scolari's frontline striker for 45 minutes.
It mattered little. Scolari had never met Martin O'Neill before and had spoken of his admiration for the teams the Villa boss has produced - but this crop simply had no chance as Chelsea gave them a first-half masterclass in passing and movement.
Villa had been billed as the team to put pressure on Chelsea's unbeaten home league record, with the pace of Gabriel Agbonlahor and Ashley Young enough to trouble most sides.
As it was, Branislav Ivanovic went untroubled on his league debut as most of the action was ahead of him.
John Terry, partnering the Serbian in central defence, said before the match that he wanted to play even if it was on one leg - and he probably could have done that in the first half, such was Chelsea's dominance.
Friedel's busy afternoon in goal for Villa started with two early saves.
The first effort was from Michael Ballack, who fizzed a drive from 25 yards, then Florent Malouda had a go from the left flank at a similar distance.
Frank Lampard had the first clear opening of the game, in the 18th minute, when Anelka found him with a cross, only for the England midfielder to head wide.
Lampard, however, set up the opener three minutes later after Curtis Davies' clearance fell to Malouda. Malouda slipped the ball inside to Lampard, who in turn helped it on to midfielder Cole.
Cole took one touch and lashed his finish past Friedel and inside the near post, his third of the season.
Anelka could have doubled the lead when he cracked a drive from 30 yards but his effort smashed against the crossbar - starting the onslaught on Friedel's goal.
The American goalkeeper parried a Lampard free-kick and also denied Malouda with another skidding drive.
He also made a double save in the 43rd minute, but could not prevent Anelka tapping in the rebound. Ashley Cole had crossed from the left, Ballack's drive and Anelka's follow up were saved - but the Frenchman made sure with his next effort.
It was Anelka's last contribution as he was taken off at the break for Di Santo, while Villa took off Davies and Luke Young, with James Milner and Carlos Cuellar coming on.
Stiliyan Petrov did have an effort saved by Petr Cech - but then there was more attacking from Chelsea.
Worryingly for England boss Fabio Capello, who was watching from the stands, was the sight of Terry dropping his shorts for treatment on his back.
Then midfielder Cole picked up his apparent foot injury and hobbled down the tunnel, with Salomon Kalou taking his place.
Wastefulness from Ballack at close range, then a brave block from Friedel to deny Kalou, kept the score down. Kalou also had an overhead strike disallowed for offside - and another goal would not have flattered the hosts.
Scolari: My most satisfying winLuiz Felipe Scolari declared victory against Aston Villa as his most satisfying
result as Chelsea boss as his side head into the international break top of the
Barclays Premier League.
"I am satisfied because we played very well,'' Scolari said. "For me it is
the most important game this season because if we won we were in first position
in the league and now we have 10 days to recuperate our players through the
international break.
"After, when we start the league, all our players will be in good
condition.''
John Terry dropped his shorts to receive treatment on his back, while Joe Cole
limped off with a foot injury - but Scolari feels they will be ready to play for
England against Kazakhstan and Belarus.
Of midfielder Cole's problem, Scolari said: "He got a little touch, it's
nothing, a little problem on the foot. In two or three days with the national
team he will be in the condition to play.
"John Terry is the same. He is a fantastic man, if he feels something he still
wants to play.''
Ashley Cole came through 90 minutes following a slight knock during the week,
although Anelka came off at the break and may miss the first part of France's
schedule.
England boss Fabio Capello watched his players from the stands, with Frank
Lampard putting in a box-to-box display in Chelsea's midfield.
"He played very, very well - I said it two times not once,'' said Scolari.
Villa boss Martin O'Neill agreed, adding: "He was absolutely outstanding. I
think he is an outstanding player.''
Villa barely tested Petr Cech in Chelsea's goal but got the glimpse of a goal
when Gabriel Agbonlahor almost took advantage of a Terry backpass.
O'Neill had no complaints with the result, adding: "Chelsea were brilliant. We
would have had to have our best players at the top of their game to compete,
never mind anything else. It is a harsh lesson.
"It's what you want to aspire to. We didn't help ourselves but it doesn't
matter. We will have learned a lot from this.''
But for the reflexes of Brad Friedel, Chelsea could have added to their two
goals in the second half.
"I was pleased he was in goal for us,'' O'Neill. "He was fantastic and we
needed him or we would have been in a spot more bother.''
Chelsea 2 - 0 Aston Villa
