Former Everton winger Andrei Kanchelskis is in contention to make his debut for Southampton against his old club at the St Mary's.
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Kanchelskis is expected to figure at some stage after joining on a free transfer last week as Saints bid for their first Barclaycard Premiership win of the season.
Manager Gordon Strachan is facing the dilemma of whether or not to risk key defender Claus Lundekvam.
Lundekvam, a regular in Strachan's team since he took charge from Stuart Gray 11 months ago, has not played since damaging his hamstring in the 3-0 defeat at Liverpool 17 days ago.
But the centre-back was included in Norway's squad for their 2-2 draw against Denmark last Saturday and successfully came through his first full training session at the start of the week.
Swedish international Michael Svensson has partnered Paul Williams in the heart of the defence in Lundekvam's absence.
But Strachan could decide to reunite his first-choice defensive pairing with Svensson ruled out of Saturday's game at West Brom as he serves a one-match ban after being sent off at Tottenham.
Strachan said: "Claus is an important player who has been excellent for us since I came but it's important that we don't rush him back too soon.
"The last thing that you want to do is bring a player back early and risk the problem getting worse.
"Michael has done well since he came into the team and he was unlucky to be sent off at Tottenham."
Swedish World Cup star Anders Svensson is expected to overcome a chest infection to continue in midfield while Latvian striker Marian Pahars is hoping for a recall in attack after being dropped to the bench for the Tottenham defeat.
Everton travel to the game with their defence almost in disarray.
Still out is goalkeeper Richard Wright with an arm injury so Steve Simonsen will continue to deputise.
Out too is Scottish international left-back Gary Naysmith with ankle ligament problems, while centre-back Alan Stubbs will be serving the one-match ban for being sent off against Birmingham two weeks ago.
New Nigerian defender Joseph Yobo, still without a first team game since he joined in the summer, has picked up another injury, this time a jarred ankle in training and a late decision will be taken on his involvement but it looks unlikely.
Full-back Alessandro Pistone is a long-term injury worry with hamstring problems, while Everton's build-up has not been helped by the abuse heaped on key defender David Weir after his part in Scotland's Euro' debacle in the Faroe Islands.
It means that Steve Watson - who has not played all season with a hamstring worry - could be drafted straight into the side at St. Mary's with David Unsworth reverting to full-back and the prospect of untried Chinese defender Li Weifeng getting closer to first team action.
Moyes has been quick to defend Weir, Everton and Scotland's most experienced defender, who has taken the brunt of the flak following the 2-2 draw in the Faroes.
"I'd need to be sure who have actually been criticising David, because people who have seen him play for Everton know he has been fantastic," he said.
"He has been great for us and maybe you should look at the circumstances of what happened to Scotland before you make any comments about him."
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